Developed by Michel Aguet, Institute of Molecular Biology I, University of Zurich in 1993. C57BL/6 background. Maintained by The Institute of Medical Science, The University of Tokyo. B6.129S7-Ifngr1<tm1Agt> B6.129S7-Ifngr1<tm1Agt> B6-Ifngr1 KO 1993年 Institute of Molecular Biology I, University of Zurich, Dr. Michel Aguetらにより開発。 AB1 ES細胞由来。C57BL/6J背景。1996年、東大医科研・高津研より導入。 129S7/SvEvBrd-Hprt<+> (AB1) herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli Neomycin resistance gene, SV40 PolyA signal, mouse Ifngr1 genomic DNA IFN gamma 1型受容体 (IFN gammna R1) 遺伝子欠損マウス。細胞内寄生性細菌等に対して易感染性。 AB1 [129S7/SvEvBrd-Hprt<+>] 1993年 Institute of Molecular Biology I, University of Zurich, Dr. Michel Aguetらにより開発。AB1 ES細胞由来。C57BL/6J背景。1996年、東大医科研・高津研より導入。129S7/SvEvBrd-Hprt<+> (AB1) Yoichiro IWAKURA In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science, 259, 1742-1745 (1993).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. Immunology and Inflammation Research IFN gamma 1 knockout mice. Homozygous mutant mice show increased susceptibility to infection. RBRC04922 <a href='https://brc.riken.jp/mus/pcr04922'>Genotyping protocol -PCR-</a> 岩倉　洋一郎 C（3〜6か月） true 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Science, 259, 1742-1745 (1993).<br>研究成果の公表にあたって謝辞の表明を必要とする。 C (3-6 months) Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> C57BL/6J (亜系統は不明)